B. coagulans is a probiotic, well known for its clinical efficacy in several human conditions. B. coagulans has been granted Qualified Presumption of Safety (QPS) status since 2008 by the European Food Safety Authority and also has GRAS status issued by USFDA.
Bacillus licheniformis is a ubiquitous organism consumed by humans for millions of years. Bacillus licheniformis is a gram-positive, spore-forming bacterium and is a close relative of Bacillus subtilis. Bacillus licheniformis is a Generally Recognized as Safe (GRAS) organism in the United States by the Food and Drug Administration (FDA) standard for safety and toxicity of bacterial strains and has Qualified Presumption of Safety (QPS) designation in the European Union (EU).
Bacillus clausii is a probiotic widely used in Italy since the1960s for viral diarrhea in children and for antibiotic associated diarrhea.
B. clausii is an aerobic, spore-forming bacterium that is able to survive transit through the acidic environment of the stomach and colonize the intestine even in the presence of antibiotics. It is said to have been identified by name in 1995 by German bacteriologist Dieter Claus.